Speckle tracking echocardiography in growth restricted fetuses.

Speckle tracking echocardiography in growth restricted fetuses. - STRAIN.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51474

Enrollment

Registered

2022-02-04

Start date

2022-02-01

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fetal growth restriction function of the heart

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: - An imminent iatrogenic preterm birth (between 24 and 34 weeks* gestation) of a growth restricted fetus, receiving antenatal steroids in the context of standard care to promote fetal lung maturation. Fetal growth restriction is defined as an abdominal circumference or estimated fetal weight =10th percentile and no abnormal Doppler findings.

Exclusion criteria

Exclusion criteria: - Age 8 hours ago before the first (baseline) ultrasound; - Pregnant patients who are unable to reasonably assess their interests in participating in the study.

Design outcomes

Primary

Measure	Time frame
Left ventricle longitudinal strain rate at baseline and after administration of antenatal steroids in growth restricted fetuses compared with appropriate for gestational age fetuses.	—

Secondary

Measure	Time frame
Other speckle tracking- and conventional hemodynamical Dopplerparameters at baseline and after administration of antenatal steroids in growth restricted fetuses compared with appropriate for gestational age fetuses. These parameters include: - Measurements on global-, transverse- and basaleapical longitudinal contractility; - Systolic-, diastolic- and global function parameters: mitral- and tricuspid annular plane systolic excursion, peak early- and late transvalvular filling velocities and left and right myocardial performance index. - Morphometric parameters (left and right sphericity index); - Pulsatility index (PI) in the uterine arteries, umbilical artery, middle cerebral artery and ductus venosus.	—

Measure

Time frame

Other speckle tracking- and conventional hemodynamical Dopplerparameters at baseline and after administration of antenatal steroids in growth restricted fetuses compared with appropriate for gestational age fetuses. These parameters include: - Measurements on global-, transverse- and basaleapical longitudinal contractility; - Systolic-, diastolic- and global function parameters: mitral- and tricuspid annular plane systolic excursion, peak early- and late transvalvular filling velocities and left and right myocardial performance index. - Morphometric parameters (left and right sphericity index); - Pulsatility index (PI) in the uterine arteries, umbilical artery, middle cerebral artery and ductus venosus.

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Countries

Netherlands

Outcome results