the MICCS study: the complex relation between the microcirculation and macrocirculation in patients after cardiothoracic surgery with and without circulatory shock

the MICCS study: the complex relation between the microcirculation and macrocirculation in patients after cardiothoracic surgery with and without circulatory shock - The MICCS study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51419

Enrollment

100

Registered

2022-10-20

Start date

2022-11-14

Completion date

Unknown

Last updated

2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiogenic and distributive shock Circulatory shock

Interventions

Included patients will undergo treatment after cardiothoracic surgery according to current clinical practice. Microcirculation measurement with the CytoCam will be performed as soon as possible afte

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Age of patient is at least 18 years - Patients are admitted to the ICU after cardiothoracic surgery

Exclusion criteria

Exclusion criteria: - Patients who refuse to take part in the study - Patients younger than 18 years - Patients with maxillofacial trauma - Patients known with tumor(s) in the mouth or throat area

Design outcomes

Primary

Measure	Time frame
Primary study outcome The primary outcome is the time course of microcirculatory parameters in patients admitted to the ICU after cardiothoracic surgery with and without circulatory shock.	—

Secondary

Measure	Time frame
Secondary study outcomes include: • The time course of microcirculatory parameters in patients admitted to the ICU after cardiothoracic surgery with and without circulatory shock • The coherence between the maicrocirculation and microcirculation in patients admitted to the ICU after cardiothoracic surgery with and without circulatory shock. Coherence meaning whether changes in microcirculatory parameters are congruent with (in the same direction of) expected changes in the microcirculation. • The relationship between the microcirculation and vital organ (dys)function, particularly the need for vasopressors and/or inotropic therapy or duration of mechanical support. • The association between microcirculation and clinical outcomes (i.e. acute kidney injury, the need for continuous venovenous hemofiltration, Iength of stay ICU and ICU mortality	—

Measure

Time frame

Secondary study outcomes include: • The time course of microcirculatory parameters in patients admitted to the ICU after cardiothoracic surgery with and without circulatory shock • The coherence between the maicrocirculation and microcirculation in patients admitted to the ICU after cardiothoracic surgery with and without circulatory shock. Coherence meaning whether changes in microcirculatory parameters are congruent with (in the same direction of) expected changes in the microcirculation. • The relationship between the microcirculation and vital organ (dys)function, particularly the need for vasopressors and/or inotropic therapy or duration of mechanical support. • The association between microcirculation and clinical outcomes (i.e. acute kidney injury, the need for continuous venovenous hemofiltration, Iength of stay ICU and ICU mortality

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Aug 25, 2026