chronic obstructive pulmonary disease
Conditions
Interventions
None listed
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • COPD, based on GOLD classification • Clinically stable according to the pulmonary physician, i.e. no exacerbation and/or hospitalization within the previous 4 weeks • Age between 40-80 years
Exclusion criteria
Exclusion criteria: • Inability to understand the Dutch language • Musculoskeletal and neurological problems influencing quadriceps muscle function testing
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be the electrically evoked isometric quadriceps muscle endurance (fatigue resistance) and voluntary isokinetic (work fatigue index5) and isometric quadriceps endurance (time to fatigue). | — |
Secondary
| Measure | Time frame |
|---|---|
| • Involuntary (electrically evoked) assessed muscle force, early and half relaxation times, 20/50 Hz ratio and normalized maximal rate of force rise (MFR) of the quadriceps • Voluntary assessed isokinetic total work and work fatigue index10 • Fatigue using the CIS-fatigue | — |
Countries
Netherlands
Outcome results
None listed