Multiple Sclerosis
Conditions
Interventions
Group I: receives no intervention, only sham TENS (CON), Group II: performs
strength exercises (SExerc), Group III: receives TENS while at rest (TENS) and
Group IV: receives TENS while performing st
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - Age: 18-65 years - EDSS (Expanded Disability Status Scale) score 30 - FSS (Fatigue Severity Scale) score > 4 or MFIS (Modified Fatigue Impact Scale) score > 38 - No known cardiovascular disorder or having a positive advice on a sport medical examination
Exclusion criteria
Exclusion criteria: - Being a participant in an exercise study - Having a psychiatric disorder - Having cognitive or communication problems which reduces the capacity to understand instructions - Planned a change in medication during the training period - Having a neurological disorder other than MS - Having cardiovascular disorders and no positive advice from a sport medical examination - Having a pacemaker or another implantable electronic apparatus. - Being pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters are changes in the scores of i) the six-minute walking test (6-MWT), ii) the perceived walking disability (MSWS-12), iii) fatigue questionnaires (FSS and MFIS) and iv) 30 second chair stand test. | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in muscle force (leg extensor and arm flexor), muscle fatigability and psychomotor speed. | — |
Countries
Netherlands
Outcome results
None listed