Artificial Intelligence driven synthetic CT to substitute CT scans of the head and neck region

Artificial Intelligence driven synthetic CT to substitute CT scans of the head and neck region - MRI-based synthetic CT images of the head and neck

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51355

Enrollment

Registered

2022-07-26

Start date

2022-09-22

Completion date

Unknown

Last updated

2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Imaging of bones in the head and neck region

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults referred for a CT-scan of the mastoid, sinonasal complex or face.

Exclusion criteria

Exclusion criteria: Pregnancy. Contra-indications for MRI or CT. Unwillingness to be informed about possible, clinically relevant, incidental findings from the MRI examination.

Design outcomes

Primary

Measure	Time frame
1. Geometrical accuracy of the bone morphology by determining the mean surface distance in mm between the cortical edges on synthetic CT and on true CT. 2. Accuracy of the voxelwise radiodensity in Hounsfield Units and accuracy of the radiodensity contrast. 3. Accuracy of the visibility of clinically relevant anatomical landmarks on the synthetic CT images compared to the corresponding true CT images in the adult population.	—

Measure

Time frame

1. Geometrical accuracy of the bone morphology by determining the mean surface distance in mm between the cortical edges on synthetic CT and on true CT. 2. Accuracy of the voxelwise radiodensity in Hounsfield Units and accuracy of the radiodensity contrast. 3. Accuracy of the visibility of clinically relevant anatomical landmarks on the synthetic CT images compared to the corresponding true CT images in the adult population.

—

Secondary

Measure	Time frame
4. Evaluation of potential usefulness of the synthetic CT images for surgical planning, surgical navigation and diagnostic purposes.	—

Countries

Netherlands

Outcome results