opname van aminozuren amino acid uptake kinetics
Conditions
Interventions
During each visit, research subjects will receive one of the three protein
concentrates (barley rice protein, pea protein or whey protein) dissolved in
water, representing a 20g protein load, in ran
Sponsors
Wageningen Food and Biobased Research
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: * Apparently healthy men and women; * Age between 18 and 40 years; * Body mass index (BMI) between 18.5 and 30 kg/m2 ; * Having veins suitable for blood sampling via a catheter (judged by study nurse/ medical doctor).
Exclusion criteria
Exclusion criteria: * Any metabolic, gastrointestinal, inflammatory or chronic disease (such as diabetes, anaemia, hepatitis, cardiovascular disease),or having a condition or disease that may lead to an impaired immune system; * History of gastrointestinal surgery or having (serious) gastrointestinal complaints; * History of liver dysfunction (cirrhosis, hepatitis) or liver surgery; * Kidney dysfunction (self-reported); * Any use of medication that may suppress the immune system, this will be judged by the medical supervisor; * Use of medication that may influence the study results, such as gastric acid inhibitors, laxatives, stomach protectors and drugs that can affect intestinal motility, this will be judged by the medical supervisor; * Anaemia (Hb values
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are total amino acid (AA) and essential amino acid (EAA) uptake kinetics e.g. the appearance of free amino acids in blood samples collected before and after the postprandial protein load. | — |
Secondary
| Measure | Time frame |
|---|---|
| Plasma glucose and insulin levels will be determined before and after postprandial protein load | — |
Countries
Netherlands
Outcome results
None listed