What is the effect of deep procedural sedation with HFNOT on tcPCO2, mitoPO2 and mitoVO2

What is the effect of deep procedural sedation with HFNOT on tcPCO2, mitoPO2 and mitoVO2 - Impact of sedation with HFNOT on tcPCO2, mitoPO2 and mitoVO2

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51298

Enrollment

Registered

2022-12-20

Start date

2023-02-16

Completion date

Unknown

Last updated

2024-04-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patienten die diepe sedatie anesthesie ondergaan met HFNOT monitored anesthetic care sedation

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Age over 18 years - Acceptable proficiency of the Dutch language - Scheduled for a procedure requiring deep procedural sedation anesthesia with HFNOT.

Exclusion criteria

Exclusion criteria: - Porphyria - Known intolerance to components of the ALA plaster - Presence of mitochondrial disease - Pregnancy/lactation - Patients with skin lesions on the measurement location which impede measurements - Incapability to provide inform consent, due to a mental condition interfering with the ability to understand the provided information

Design outcomes

Primary

Measure	Time frame
- To examine the effects of HFNOT during deep procedural sedation on the tcPCO2 - To determine the effects of HFNOT during deep procedural sedation on the mitoPO2	—

Secondary

Measure	Time frame
- To examine the effect of deep procedural sedation with HFNOT on the mitoVO2 - To study the relationship between the tcPCO2 and the standard hemodynamic and respiratory parameters used during deep procedural sedation. o Non-invasive blood pressure o Peripheral Oxygen Saturation o Heart Rate o Respiratory Rate - To evaluate the relationship between the mitoPO2 and the standard hemodynamic and respiratory parameters used during deep procedural sedation. o Non-invasive blood pressure o Peripheral Oxygen Saturation o Heart Rate o Respiratory Rate	—

Measure

Time frame

- To examine the effect of deep procedural sedation with HFNOT on the mitoVO2 - To study the relationship between the tcPCO2 and the standard hemodynamic and respiratory parameters used during deep procedural sedation. o Non-invasive blood pressure o Peripheral Oxygen Saturation o Heart Rate o Respiratory Rate - To evaluate the relationship between the mitoPO2 and the standard hemodynamic and respiratory parameters used during deep procedural sedation. o Non-invasive blood pressure o Peripheral Oxygen Saturation o Heart Rate o Respiratory Rate

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Countries

Netherlands

Outcome results