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Training Reappraisal under Stress

Training Reappraisal under Stress - TRuSt

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON51282
Enrollment
128
Registered
2022-10-26
Start date
2022-11-08
Completion date
Unknown
Last updated
2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stress-gerelateerde klachten stress-related mental health problems

Interventions

To reduce the burden on participants, instead of inviting them regularly to the lab to do the training, we will use a smartphone-based training that participants can easily follow in their daily liv

Sponsors

Radboud Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers between 18 and 35 years Right-handed Normal uncorrected hearing Normal or corrected-to-normal vision

Exclusion criteria

Exclusion criteria: Pregnancy Contraindications for MRI scanning (e.g. pacemaker, implanted metal, claustrophobia) Current or history of any psychiatric disorder Disorders of the autonomic system Disorders of the endocrine system Body mass index lower than 18 or higher than 30

Design outcomes

Primary

MeasureTime frame
The main study endpoint is to assess the effectiveness of emotion regulation under acute stress after a cognitive reappraisal training, which is operationalized as the successful downregulation of negative affect in response to negative pictures when applying the trained emotion regulation strategy. We predict successful downregulation of negative affect under acute stress in the training but not in the no training group.

Secondary

MeasureTime frame
In addition, by means of functional MRI, we want to investigate the associated neural mechanisms underlying effective emotion regulation under acute stress after a cognitive reappraisal training vs. no such training. We will also investigate psychophysiological reactions as a secondary outcome measure of effective emotion regulation (corrugator electromyography [cEMG], skin conductance responses [SCRs], pupil dilation responses [PDRs]).

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)