EUS-guided choledochoduodenostomy (versus ERCP) for primary drainage of malignant distal biliary obstruction: a pilot study

EUS-guided choledochoduodenostomy (versus ERCP) for primary drainage of malignant distal biliary obstruction: a pilot study - SCORPION-pilot study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON51255

Enrollment

Registered

2021-09-22

Start date

2021-10-13

Completion date

Unknown

Last updated

2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Biliary obstruction (malignant)

Interventions

All patients will be treated with the investigational treatment (EUS-CD).

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Radiographically (CT, EUS) distal malignant bile duct obstruction - Histology or cytology proven malignancy of the primary tumour or metastasis; onsite cytology evaluation after EUS guided fine-needle sampling that is highly suspected of a malignancy suffices - Indication for biliary drainage; in case of an resectable tumour this should be discussed during a clinical multidisciplinary meeting - Written informed consent

Exclusion criteria

Exclusion criteria: - Age 1.5 or platelets

Design outcomes

Primary

Measure	Time frame
The primary endpoint is technical success.	—

Secondary

Measure	Time frame
Secondary endpoint are clinical success, procedural time, adverse events, stent patency, need for reinterventions, technical outcome at pancreaticoduodenectomy (when applicable), and cost.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jul 23, 2026