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Better control and treatment of Atopic Dermatitis disease by exploring the universe of microenvironment imposed tissue signatures and their correlates in liquid biopsies

Better control and treatment of Atopic Dermatitis disease by exploring the universe of microenvironment imposed tissue signatures and their correlates in liquid biopsies - ImmUniverse WP6 AD

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON51252
Enrollment
60
Registered
2021-09-28
Start date
2022-06-30
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

eczema topic dermatitis

Interventions

None listed

Sponsors

Radboud Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Age >= 18 years at time of study entry 2. Written Informed Consent. 3. Diagnosis of chronic atopic dermatitis for at least 1 year prior to enrollment 4. Use of licensed targeted immuno therapy within routine care

Exclusion criteria

Exclusion criteria: 1. Experiencing or history of other concomitant skin condition that would interfere with evaluations of the effect of medication on atopic dermatitis. 2. Patients with a tendency to develop hypertrophic scars

Design outcomes

Primary

MeasureTime frame
Molecular stratification tools and *hard* molecular endpoints for disease control on the individual patient level. Aanalysis of tissue-derived signatures with *circulating signatures* detectable in liquid biopsies (bood and tissue liquids), employing state-of-the-art profiling technologies corresponding to multi-Omics datasets.

Secondary

MeasureTime frame
Not applicable.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)