Macrophages and monocytes in uncomplicated pregnancy and fetal growth restriction

Macrophages and monocytes in uncomplicated pregnancy and fetal growth restriction - Macrophages, monocytes and fetal growth restriction

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51245

Enrollment

Registered

2021-07-05

Start date

2023-06-21

Completion date

Unknown

Last updated

2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fetal growth problems Fetal growth retardation

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Informed consent - 18-40 years old - Pregnant - Gestational age (GA): 36-42 weeks - Fetal growth restriction OR appropriate fetal growth

Exclusion criteria

Exclusion criteria: - Smoking - Immune related disorders - Fever/illness within the last month - Fertility treatment (ovulation induction, intra-uterine insemination, IVF-ICSI) - Major congenital abnormalities

Design outcomes

Primary

Measure	Time frame
Number and phenotype of macrophages and monocytes in maternal blood, placenta and cord blood	—

Secondary

Measure	Time frame
Functional status of macrophages and monocytes: cytokine secretion and response to pro- and anti-inflammatory triggers	—

Countries

Netherlands

Outcome results