blood cholesterol levels
Conditions
Interventions
Research subjects will receive 4 slices/buns of bread per day, representing a
Kori-tofu dose of 34.5 gram or a matched reference (incl. whey protein, soy oil
to and maltodextrin/cellulose), in rando
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Age between 40-70 years; * BMI between 18.5-35 kg/m2; * Total cholesterol levels >5 mmol/L or LDL >3 mmol/L
Exclusion criteria
Exclusion criteria: * Use of medication/supplements/food items that may influence the study results, such as cholesterol lowering medication, Becel ProActiv (judged by our research physician); * Total cholesterol levels >7 mmol/L; * LDL cholesterol levels >5 mmol/L; * Reported slimming, medically prescribed or other extreme diets; * Reported weight loss or weight gain of >5 kg in the month prior to pre-study screening; * Not willing to give up blood donation during the study; * Current smokers; * Alcohol intake *4 glasses of alcoholic beverages per day; * Pregnant, lactating or wishing to become pregnant in the period of the study (self-reported); * Abuse of drugs; * Food allergies or intolerances for products that we use in the study; * Participation in another clinical trial at the same time; * Being an employee of the Food, Health & Consumer Research group of Wageningen Food & Biobased Research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters are fasting total and LDL cholesterol levels. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study outcomes are blood pressure and other markers of lipid metabolism, namely: HDL cholesterol, triglycerides levels, leptin and adiponectin. Secondary study outcomes also include markers of glucose metabolism: plasma insulin levels, HbA1c, fructosamine and glucose. | — |
Countries
Netherlands
Outcome results
None listed