obesity Overweight
Conditions
Interventions
The intervention group will receive mini drinks (100 mL) containing 2g plant
stanols each (present as plant stanol esters esterified to rapeseed oil) and
are required to take two drinks daily in ord
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Men and women, 18 years or older, BMI 27-35 kg/m2, not using products with added plant sterols or plant stanols, willing to abstain from products with added plant sterols or plant stanols during study, willing to keep intake of fish oil and vitamin supplements constant during study
Exclusion criteria
Exclusion criteria: Already received COVID-19 vaccination, already had a positive test for COVID-19 (all tests, e.g. PCR test or antibody test), allergy to an ingredient of the mini drinks, excessive alcohol use (>20 consumptions per week), regular use of drugs, blood donors that want to donate one month prior to or during the study, pregnant or breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint is vaccination response to a COVID-19 vaccine. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints include amongst others hematological, inflammatory and immunological parameters (e.g. hs-CRP, leukocyte differential count) and metabolic markers (e.g. blood lipid profiles, plasma glucose, serum insulin, HOMA-IR). | — |
Countries
Netherlands
Outcome results
None listed