panic disorder | burnout
Conditions
Interventions
A single reactivation of panic symptoms at work through hyperventilation
provocation, followed by the oral administration of 40 mg of the noradrenergic
*-blocker propranolol.
Sponsors
TNO
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. aged between 18 and 65 years; 2. a score of > 8 on the Panic Disorder Severity Scale; 3. a score of > 2.79 on both the core symptoms and secondary symptoms of the work-related version of the Burnout Assessment Tool; 4. a score of at least 4 on the panic and anxiety item of the BAT.
Exclusion criteria
Exclusion criteria: 1. other relevant treatment for panic symptoms or burnout within 3 months before start of the study; 2. life-time psychosis; 3. depression; 4. current state of asthma or COPD, which necessitates medication use; 5. cardiovascular diseases or irregular heartbeat; 6. hypotension or hypertension; 7. pregnancy or breastfeeding; 8. epilepsy; 9. any medication contra-indicative of the use of propranolol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Our primary output will be the decrease in frequency and severity of panic symptoms, from screening to post-treatment and follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Our secondary output will be the decrease in the levels of burnout, from screening to post-treatment and follow-up. | — |
Countries
Netherlands
Outcome results
None listed