opname van eiwitten protein digestion
Conditions
Interventions
Research subjects will receive two times an easy digestible protein source wey
and three times a poorly digestible protein source lucerne. Both representing a
20g protein load.
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: * Apparently healthy men and women; * Age between 18 and 40 years; * Body mass index (BMI) between 18.5 and 30 kg/m2 ; * Having veins suitable for blood sampling via a catheter (judged by study nurse/ medical doctor).
Exclusion criteria
Exclusion criteria: * Any metabolic, gastrointestinal, inflammatory or chronic disease (such as diabetes, anaemia, hepatitis, cardiovascular disease),or having a condition or disease that may lead to an impaired immune system * History of gastrointestinal surgery or having (serious) gastrointestinal complaints; * History of liver dysfunction (cirrhosis, hepatitis) or liver surgery; * Kidney dysfunction (self-reported); * Any use of medication that may suppress the immune system, this will be judged by the medical supervisor; * Use of medication that may influence the study results, such as gastric acid inhibitors, laxatives, stomach protectors and drugs that can affect intestinal motility, this will be judged by the medical supervisor; * Anaemia (Hb values
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is AA uptake kinetics e.g. the appearance of free amino acids in blood samples collected before and after consumption. We will determine and quantify between, and within-subject variability. | — |
Secondary
| Measure | Time frame |
|---|---|
| GI complaints via questionnaire | — |
Countries
Netherlands
Outcome results
None listed