Hemodynamiek, intraoperatief en tijdens intensive care opname Hypotension low blood pressure
Conditions
Interventions
The intervention used in the treatment arm will consist of: HemoSphere with
Acumen IQ variables including HPI and diagnostic guidance. HPI will be
calculated via Acumen IQ sensor connected to the ra
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Aged 18 years or older at inclusion • Planned for elective on-pump CABG surgery or CABG with additional single heart valve surgery (e.g. valve repair or replacement) • Planned to receive standard monitoring for cardiac surgery • Target MAP of 65 mmHg or above during surgery (excluding pump time) and mechanically ventilated duration of ICU admission
Exclusion criteria
Exclusion criteria: • Known cardiac shunts (significant) • Severe cardiac arrhythmias (including but not limited to persistent atrial fibrillation prior to surgery) • Expected to receive a hemodynamic assist device (e.g. intra-aortic balloon pump) during surgery • Dialysis dependent kidney failure prior to surgery • Planned to receive Perioperative Goal Directed Therapy (PGDT) other than standard intraoperative care • Previous cardiac surgery in medical history
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The overall TWA of hypotension during both the off-pump phases of on-pump CABG surgery and the mechanically ventilated phase of post-operative ICU admission (or 8 hours maximum) | — |
Secondary
| Measure | Time frame |
|---|---|
| All secondary objectives will be analyzed for the overall duration of both the off-pump phases of on-pump CABG surgery and the mechanically ventilated phase of post-operative ICU admission (or 8 hours maximum): • Incidence of hypotension • Time spent in hypotension • The percentage of time in hypotension • The area under the curve (AUC) of a MAP | — |
Countries
Netherlands
Outcome results
None listed