Ketoacid ingestion along with protein to attenuate muscle catabolism during hemodialysis

Ketoacid ingestion along with protein to attenuate muscle catabolism during hemodialysis - Ketoacids during hemodialysis (KIC-HD)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51089

Enrollment

Registered

2021-03-30

Start date

2021-06-07

Completion date

Unknown

Last updated

2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Eiwitmetabolisme in het hele lichaam Muscle wasting protein-energy wasting syndrome

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Aged >18 years - Ability to provide written informed consent - Hemodialysis treatment for >3 months - Well-functioning arteriovenous shunt in upper or lower arm

Exclusion criteria

Exclusion criteria: - Hospitalization 200/100mm Hg) or arrhythmia - Previous episodes of intradialytic hypotension related to food intake - Allergies to milk proteins - Dysphagia - Pregnancy - Cognitive disorders

Design outcomes

Primary

Measure	Time frame
The primary endpoint in this study will be the net AA balance over the forearm, calculated by subtracting the venous from arterial AA concentrations.	—

Secondary

Measure	Time frame
Secondary study parameters include plasma and breath L-(ring-13C6)-phenylalanine enrichments and AA concentrations in spent dialysate.	—

Countries

Netherlands

Outcome results