Parkinson Tremor
Conditions
Interventions
The intervention involves subtle mechanical vibrations (vibrotactile
stimulation) on the wrist or ankles. This is a non-invasive and painless way to
provide somatosensory stimuli, in a continuous (8
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: -18-80 years old -Have a diagnosis of idiopathic PD made by a movement disorders specialist. -Medically optimized without planned medication changes for the duration of the study. -Resting tremor subscore >//
Exclusion criteria
Exclusion criteria: -The presence of additional neurologic diseases that might confound testing or the coexistence of PD and essential tremor together (action tremor that was present prior to the development of parkinsonism). -Moderate to severe peripheral neuropathy (reduced vibratory sensation) -Montreal cognitive assessment (MoCA) score
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effect of vibrotactile stimulation at tremor frequency on tremor severity (delta tremor power between stimulation and baseline). | — |
Secondary
| Measure | Time frame |
|---|---|
| The effect of continuous vibrotactile stimulation, stimulation at 1.5 times tremor frequency and sham on tremor severity (delta tremor power between stimulation/sham and baseline). The effect of continuous vibrotactile stimulation on bradykinesia (average button presses per second in the keyboard finger tapping test during stimulation versus sham). The effect of vibrotactile stimulation at step frequency on gait, with three outcome measures of Timed up and go performance: Time to complete, number of freezing episodes and duration of freezing episodes. | — |
Countries
Netherlands
Outcome results
None listed