constipation obstruction
Conditions
Interventions
All participants are asked to fast at least 4 hours (3 hours for babies
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
No minimum to 99 Years
Inclusion criteria
Inclusion criteria: All subjects: babies/children 18 years. For patients
Exclusion criteria
Exclusion criteria: All subjects: - For adults: BMI > 27 kg/m2 - For babies/children: weight for length > 2.5 standard deviation of WHO Child Growth Standard - Pregnancy - Diabetes - Any food intolerance - Intestinal stoma - Continuous tube feeding Healthy controls: - Any known gastro-intestinal disorders - Use of laxatives in the past two years Patients: - (partially) resected small intestines and/or colon - inflammatory bowel diseases
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary study parameter is the relative power increase (pre-prandial vs. post-prandial) of the EEnG signal (in mV/Hz^2) in the relevance frequency region for colonic motility. This power increase can then be compared between healthy subjects and patients to investigate whether colonic motility can be measured using EEnG and also whether EEnG could be used as diagnostic tool for colonic motility disorders. | — |
Secondary
| Measure | Time frame |
|---|---|
| The questionnaires are summarized in a grand total score, which can be used to compare the burden of the EEnG procedure with the Gold Standard procedures. | — |
Countries
Netherlands
Outcome results
None listed