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Articulation and coordination of speech after treatment for oral cancer

Articulation and coordination of speech after treatment for oral cancer - Speech difficulties after oral cancer treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON51026
Enrollment
40
Registered
2021-05-25
Start date
2021-09-28
Completion date
Unknown
Last updated
2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dysarthria speech pathology

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • At least 18 years of age and able to make an informed consent • Native speaker of Dutch • Diagnosed with oral tumors and having had a major surgical resection of a TNM stage T3 or T4, where parts of the tongue or jaw have been removed and perhaps replaced by other tissue at least 12 months before (patient subject) or a volunteer without disturbed speech.

Exclusion criteria

Exclusion criteria: • Recurrence of disease • History of neurological or psychological disorders • Self-reported signs of depression • Stuttering or other pre-existing speech and language problems • Anatomy that prevents attaching sensors to the tongue (i.e., trismus or tongue immobility) • Problems with sight or hearing that impede reading or understanding instructions. When glasses or a hearing aid resolve these problems, there is no impediment to participation. • Non removable metal on, in or close to the head (e.g., piercings, dental braces, medical devices such as deep brain stimulation electrodes) or medical devices (e.g., a pacemaker) incompatible to electromagnetic fields.

Design outcomes

Primary

MeasureTime frame
- Displacement of the tongue tip, the tongue body, the lips and the jaw at consonant and vowel targets - Velocity of tongue, of the tongue tip, the tongue body, the lips, and the jaw at key landmarks of speech gestures. - Duration of speech gestures produced with the tongue tip, the tongue body, the lips and the jaw. - Speech rate (syllables/min and words/min)

Secondary

MeasureTime frame
- Acoustic measures of speech - Models to link articulation and speech, both speech synthesis from EMA, and EMA from speech (machine learning) - Changes in the variability and complexity of articulators* movement under masked auditory feedback compared to normal feedback

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)