Bone blood perfusion of the patella with non-invasive spectroscopy in patients with patellofemoral pain

Bone blood perfusion of the patella with non-invasive spectroscopy in patients with patellofemoral pain - Bone perfusion with non-invasive spectroscopy in patellofemoral pain

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51022

Enrollment

Registered

2021-07-09

Start date

2022-02-17

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

orthopedische klacht (surmenage, patellofemorale pijn) patellofemoral pain syndrome

Interventions

None listed

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: cases: patellofemoral pain for at least 3 months and minimum pijn score (VAS 3/10) controls: no complaints or surgery in the past (in the leg)

Exclusion criteria

Exclusion criteria: cases and controls: specific knee disorders like meniscus or ligament injury (e.g. ACL)

Design outcomes

Primary

Measure	Time frame
Main outcome measures are changes in oxygenated hemoglobine concentrations (O2Hb), deoxygenated hemoglobine concentrations (HHb), total hemoglobine (THb) and tissue saturation index (TSI). Those parameters will be determined in two protocols, with protocol 1 simulating prolonged sitting and protocol 2 simulating descending stairs. Differences in changes between healthy subjects and patients with PFP will be investigated.	—

Measure

Time frame

Main outcome measures are changes in oxygenated hemoglobine concentrations (O2Hb), deoxygenated hemoglobine concentrations (HHb), total hemoglobine (THb) and tissue saturation index (TSI). Those parameters will be determined in two protocols, with protocol 1 simulating prolonged sitting and protocol 2 simulating descending stairs. Differences in changes between healthy subjects and patients with PFP will be investigated.

—

Secondary

Measure	Time frame
Anterior Knee Pain Scale * Dutch Version (AKPS-DV), 13 item questionnaire Tegner Score, 10 item level of physical activity blood pressure prepatellair skinfold thickness measured with Harpenden skinfold caliper patella width measured with caliper Decline step-down test (DSDT) measuring pain-free flexion angle Lower limb range of motion (LLROM) measuring soft tissue flexibility of the kinetic chain Visual Analogue Scale (VAS) measuring pain intensity while performing protocol 1 and 2	—

Measure

Time frame

Anterior Knee Pain Scale * Dutch Version (AKPS-DV), 13 item questionnaire Tegner Score, 10 item level of physical activity blood pressure prepatellair skinfold thickness measured with Harpenden skinfold caliper patella width measured with caliper Decline step-down test (DSDT) measuring pain-free flexion angle Lower limb range of motion (LLROM) measuring soft tissue flexibility of the kinetic chain Visual Analogue Scale (VAS) measuring pain intensity while performing protocol 1 and 2

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Countries

Netherlands

Outcome results