botgezondheid Bone health osteoporosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Male Age *18 and *35 years. BMI *18.5 and *27.5 kg/m2 Willing to give blood samples
Exclusion criteria
Exclusion criteria: * Blood donation during the study period * Currently smoking * Severe allergy to nuts or intolerance to gluten, as supplements are being produced in factory that may have used nuts or gluten previously * Consumption of >21 alcoholic beverages per week * Use of antibiotics in the past month * Medical condition that can interfere with the study outcome (i.e. cardiovascular disease, pulmonary disease, rheumatoid arthritis, orthopaedic disorders, renal disease, liver disease, diabetes mellitus, inflammatory disease, cognitive impairment, and thyroid or parathyroid disease)) * Use of medications known to interfere with selected outcome measures (i.e. corticosteroids, , statins, fenofibrate, beta-blocker) * (Chronic) injuries of the locomotor system that can interfere with the intervention. * Current participation in another biomedical research study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone turnover markers: P1NP and B-CTX | — |
Secondary
| Measure | Time frame |
|---|---|
| Parathyroid hormone, testosterone, calcium | — |
Countries
Netherlands