Exploring the potential of finger prick blood for assessment of BIOmarkers for LOw Grade Inflammation and CVD risk

Exploring the potential of finger prick blood for assessment of BIOmarkers for LOw Grade Inflammation and CVD risk - BIOLOGIC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON51003

Enrollment

Registered

2021-06-28

Start date

2021-07-08

Completion date

Unknown

Last updated

2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

obesity

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Age 18-70 years * Living in the surroundings of Wageningen (max. 25 km) * Stable body weight for past 6 months * Suitable veins for insertion of cannula -Specifically for lean subjects: * BMI 18.5-22 kg/m2 -Specifically for obese subjects: * BMI * 30 kg/m2

Exclusion criteria

Exclusion criteria: * Use of cholesterol-lowering medication * Use of diabetes medication (e.g. insulin, metformin) * Use of antibiotics or anti-inflammatory medication * Known allergy for any of the food components used in the study (milk, cream, sugars) * Blood clotting disorders * Current smokers * Alcohol consumption of > 21 units per week

Design outcomes

Primary

Measure	Time frame
Plasma levels of ApoB48 and LPS in both venous blood samples and finger prick blood collected under fasting conditions and in response to a high fat challenge test (1, 2, 4 and 6 hours post ingestion).	—

Countries

Netherlands

Outcome results