Submaximal cardiopulmonary exercise testing in patients with knee osteoarthritis scheduled for total knee arthroplasty: a feasibility study.

Submaximal cardiopulmonary exercise testing in patients with knee osteoarthritis scheduled for total knee arthroplasty: a feasibility study. - Feasibility of CPET in patients prior to TKA.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON50982

Enrollment

Registered

2021-03-18

Start date

2021-05-07

Completion date

Unknown

Last updated

2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gonarthrosis knee osteoarthritis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * The patient is scheduled for primary unilateral TKA surgery in MUMC+ or St. Anna Hospital; * Diagnosis of OA; * CPET can be performed three to six weeks before TKA surgery following the preoperative screening; * Mastery of the Dutch language.

Exclusion criteria

Exclusion criteria: * Undergoing revision arthroplasty, bilateral TKA or hemi-arthroplasty surgery; * Contraindications for CPET according to the American Thoracic Society (ATS) Statement on CPET and following the American Heart Association/American College of Sports Medicine (AHA/ACSM) Health/Fitness facility preparticipation screening questionnaire; * Unable to get on and off a stationary bike; * Complete dependence on a wheelchair; * Serious comorbidities (e.g. malignancy, stroke); * Cognitive impairments; * Unable to sign informed consent.

Design outcomes

Primary

Measure	Time frame
Feasibility of CPET will be assessed against five criteria: 1) recruitment rate 20%; 2) CPET performance rate 90%; 3) 90% of participants reached the VAT; 4) no serious adverse events; and 5) 80% of participants had a positive attitude towards CPET.	—

Secondary

Measure	Time frame
Aerobic capacity is determined by the VO2 at the VAT and the oxygen uptake efficiency slope (OUES).	—

Countries

Netherlands

Outcome results