Muscle and connective tissue research (no disorders) Muscle health Skin health
Conditions
Interventions
Participants will perform unilateral resistance exercise followed by the
ingestion of either 30 g of collagen peptides, 30 g free amino acids (matching
the profile of collagen peptides), or a non-ca
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Males and females - Aged between 18-35 years - Healthy, recreationally active (participating in recreational sports activities * 3 times per week) - BMI 18.5 - 30 kg/m2 - No physical limitations (i.e. able to perform all activities associated with daily living in an independent manner).
Exclusion criteria
Exclusion criteria: - Pregnant - Third generation oral contraceptives - Hormone replacement therapy - Smoking - Musculoskeletal disorders - Use of any medications known to affect protein metabolism (i.e. corticosteroids, non-steroidal anti-inflammatories, or prescribed acne medications). - Participation in any structured regular exercise program - Chronic use of gastric acid suppressing medication or anti-coagulants - Unstable weight over the last three months - Pathologies of the gastrointestinal tract - Blood donation in the past 2 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the impact of collagen peptides versus free amino acid ingestion after exercise on myofibrillar and connective tissue protein synthesis rates in muscle tissue obtained during recovery from exercise in vivo in humans. | — |
Secondary
| Measure | Time frame |
|---|---|
| - To assess the impact of collagen peptides versus free amino acid ingestion on connective tissue protein synthesis rates in skin. - To characterize plasma amino acid availability following ingestion of collagen protein versus free amino acids. | — |
Countries
Netherlands
Outcome results
None listed