Parkinson Parkinson's disease
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Diagnosis Parkinson*s disease, as confirmed by a neurologist specialized in Parkinson*s Disease, by the UK-Brain Bank Criteria. - Disease duration between 35-60 months, measured after time of diagnosis. - Active driver - Own a car or have access to a car - Age 18 to 75 - Dutch speaking - Willingness to cooperate and sign written informed consent
Exclusion criteria
Exclusion criteria: - Suffering from severe motion sickness; motion sickness is a risk factor for simulator sickness. - Use of category III medication, that may - according to current legislation - interfere with FTDr. The website www.rijveiligmetmedicijnen.nl will be used to check the classification of medication. - Presence of premorbid pathology, i.e. experienced cerebral infarction or chronic depression, non-related to Parkinson*s disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint will be a cut-off score on the MoCA which has high, preferably 100% sensitivity and reasonable specificity (>70%) in predicting the failure on the CBR on-road driving assessment. | — |
Secondary
| Measure | Time frame |
|---|---|
| The study sample will be divided into a pass and fail group, based on the on-road driving assessment. Groups will be compared in terms of age, disease severity, and performance on motor-, cognitive- and driving simulator tests. In addition, regression analyses will be used to detect predictors for failing on-road driving assessment. | — |
Countries
Netherlands
Outcome results
None listed