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The role of pregnancy on susceptibility and antibody dependent enhancement of immune cells for Zika virus infection

The role of pregnancy on susceptibility and antibody dependent enhancement of immune cells for Zika virus infection - Zika virus and pregnancy

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON50935
Enrollment
40
Registered
2021-03-30
Start date
2021-04-13
Completion date
Unknown
Last updated
2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Zika virus

Interventions

None listed

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Pregnancy

Exclusion criteria

Exclusion criteria: Pregnancy complications

Design outcomes

Primary

MeasureTime frame
The main endpoints of this study are the ZIKV titers measured in the supernatant of infected PBMCs as well as the percentage of PBMCs that are infected with ZIKV.

Secondary

MeasureTime frame
The secondary endpoints of this study are the cytokines detected in the supernatant of infected PBMCs from pregnant women and non pregnant women.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)