The effect of bile acid binding with colesevelam on postprandial glucose concentrations in patients after RYGB and cholecystectomy : a meal test study

The effect of bile acid binding with colesevelam on postprandial glucose concentrations in patients after RYGB and cholecystectomy : a meal test study - Colesevelam hypOglycemia Bile acid binding in Rygb: a meAl test study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON50934

Enrollment

Registered

2021-10-11

Start date

2022-05-02

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post bariatric hypoglycemia hypoglycemia after gastric bypass surgery

Interventions

Colesevelam tablet 625 mg (Cholestagel®) 3750 mg once dosed dissolved in water

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: patients 20-60 years, 2 years or more after RYGB and with a history of a cholecystectomy

Exclusion criteria

Exclusion criteria: known with post bariatric hypoglycemia (former) diabetic hypertriglyceridemia renal or liver disease addiction behaviour medication use that will be interfered ith by colesevelam pregnancy (planning) bowel or choledochusobstruction

Design outcomes

Primary

Measure	Time frame
Glucose nadir during the MMT in mmol/L	—

Secondary

Measure	Time frame
During the MMT : Number of patients with a hypoglycemic episode (glucose	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)