FindTrial
Sign In

The *Continuous peripherAl neRve blockadE FoR lowEr limb surgEry* (CAREFREE) trial

The *Continuous peripherAl neRve blockadE FoR lowEr limb surgEry* (CAREFREE) trial - The CAREFREE trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON50914
Enrollment
42
Registered
2021-03-25
Start date
2021-09-17
Completion date
Unknown
Last updated
2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pijnbehandeling discomfort Postoperative pain

Interventions

The proposed intervention in this study constitutes an organizational change. Research subjects randomized to *fast-track recovery* participate in a novel perioperative treatment pathway. In the int

Sponsors

Academisch Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Scheduled for elective, inpatient lower limb surgery Aged eighteen years or older Willing and able to provide written informed consent Able to handle cPNB and equipment

Exclusion criteria

Exclusion criteria: Polytrauma patients Emergency surgery Surgery for (bone) infections Severe renal and/or hepatic insufficiency Allergy to local anesthetics (Suspected) pregnancy Daycare surgery ASA 4 or higher Chronic use of opioids (> 3 months)

Design outcomes

Primary

MeasureTime frame
Patient-reported overall benefit of analgesia, as measured by the Overall Benefit of Analgesic Score (OBAS).—

Secondary

MeasureTime frame
Healthcare costs, productivity costs, postoperative opioid consumption, length of hospital stay, incidence of CPSP, postoperative pain, quality of recovery, and adverse events.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Aug 9, 2026