post-traumatic arthrosis post-traumatic osteoarthritis joint degeneration after injury
Conditions
Interventions
questioniare 
physical exam of the kneeintra-articulair joint puncture for synovial fluid aspiration
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 10 patients with hemarthrosis 10 patients without hemarthrosis -18 years or older -Recently suffered an injury of the index knee (rotational or hyperextension) -A swollen kneejoint -Inability to mobilise
Exclusion criteria
Exclusion criteria: - Patients with an active inflammatory or infectious comorbid disease (including rheumatic diseases) - Patients with knee prosthesis - Patients with coagulation disorders - Patients with a history of a cruciate ligament or meniscal injury of the index knee - Patients with a tibiofemoral fracture due to current distorsion
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The anti-inflammatory capacities of ASC*s in synovial fluid that contains blood as a result of hemarthrosis after knee injury compared to the anti-inflammatory capacities of ASC's in synovial fluid that does not contain blood. | — |
Secondary
| Measure | Time frame |
|---|---|
| - The natural course of pro-inflammatory factors levels and hemarthrosis related factor levels in the first weeks after trauma - The correlation between pro-inflammatory factors and hemarthrosis - The correlation between levels of pro-inflammatory factor levels and hemarthrosis related factor levels with the clinical presentation on the endpoints: swelling, pain and function impairment | — |
Countries
Netherlands
Contacts
Public ContactB.J. Evers
Radboud Universitair Medisch Centrum
Outcome results
None listed