Transcranial Magnetic Stimulation Mapping using the Pseudorandom Walk Method to Measure Training-Induced Plasticity

Transcranial Magnetic Stimulation Mapping using the Pseudorandom Walk Method to Measure Training-Induced Plasticity - TMS motor mapping

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON50874

Enrollment

Registered

2021-03-23

Start date

2021-03-15

Completion date

Unknown

Last updated

2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Brain plasticity in healthy participants CVA Stroke

Interventions

Motor learning of a complex upper-limb motor task - throwing of darts

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy Aged 18-55 years Right-handed

Exclusion criteria

Exclusion criteria: History of neurological or psychiatric disorders Implants or metal parts in the head Use of psychoactive drugs in the last month Pregnancy

Design outcomes

Primary

Measure	Time frame
Motor learning: Accuracy on the motor task. Motor maps: The area, volume, and centre of gravity of the muscle cortical representations for the MD and the BR muscles. Potential change will serve as a measure of cortical plasticity after motor learning. MEP-amplitude ratio: Measure for brain excitability. The height of the MEP amplitudes will be measured at a constant stimulation intensity.	—

Secondary

Measure	Time frame
Muscle synergies: The extent to which the motor maps overlap. Intermanual transfer: Potential change in the motor maps of the hemisphere that is not undergoing the intervention.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)