Respiratory distress ventilation
Conditions
Interventions
In both groups supplemental oxygen will be titrated by the OxyGenie automated
oxygen controller for 25 hours, either titrated to a target range of 91%-95% or
92%-96%. Automated oxygen control aimed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Inclusion criteria
Inclusion criteria: Born between 24-32 weeks of gestation receiving respiratory support and supplemental oxygen (at least 25%), with written informed parental consent.
Exclusion criteria
Exclusion criteria: Major congenital anomalies or arterial hypotension requiring vasopressor therapy within 48 hours prior to enrolment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of two target ranges (91%-95% and 92%-96%) while on automated oxygen control while using the OxyGenie controller on the frequency of hypoxic episodes (SpO2 | — |
Secondary
| Measure | Time frame |
|---|---|
| - To compare the effect of two target ranges (91%-95% and 92%-96%) while on automated oxygen control by using the OxyGenie controller on parameters of oxygenation: a) Distribution of oxygen saturation (the SpO2 histogram). b) Proportion of time in hypoxaemia and hyperoxaemia (varying degrees). c) Frequency and duration of hypoxaemic and hyperoxaemic episodes, and of bradycardia. (defined as a heartrate | — |
Countries
Netherlands
Outcome results
None listed