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Longkankernet implementation ctDNA Analysis

Longkankernet implementation ctDNA Analysis - LICA

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON50777
Enrollment
250
Registered
2021-05-17
Start date
2021-07-07
Completion date
Unknown
Last updated
2024-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

None listed

Sponsors

Radboud Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Patients with confirmed or suspected non-small cell lung cancer • Signed informed consent • Adult (>= 18 years of age) and mentally competent

Exclusion criteria

Exclusion criteria: • Patients with a benign lesion • Patients with a metastasis of another primary cancer than lung cancer

Design outcomes

Primary

MeasureTime frame
The primary aim of this study is to implement the ctDNA analysis to identify actionable targets in lung tumors. We envision this study will create awareness in regional hospitals with this novel test method.

Secondary

MeasureTime frame
1. Percentage of patients identified as having an activating and targetable genetic alteration as determined by tissue and liquid biopsies with an intra-individual comparison of the presence of driver mutations detected in tissue and liquid biopsies. 2. To get insight in the time it takes from diangosis to start of targeted treatment. 3. The percentage of patient with inadequate tissue for analysis where ctDNA may be an alternative. 4. Exploring cost- effectiveness

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)