Noninvasive measurement of mitochondrial oxygen tension (mitoPO2) compared to continuous hemoglobin-monitoring during massive hemorrhage in major surgery.

Noninvasive measurement of mitochondrial oxygen tension (mitoPO2) compared to continuous hemoglobin-monitoring during massive hemorrhage in major surgery. - NiMMOT

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON50764

Enrollment

Registered

2018-02-13

Start date

2018-02-26

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bloodloss during surgery blood loss hemorrhage

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: > 18 years of age at start of the study Planed for elective major surgery (abdominal, orthopaedic and gynaecologic) with a possible need for blood transfusion.

Exclusion criteria

Exclusion criteria: * Not able to read or speak Dutch or English * Skin defects at the measurement side. * Mentally disabled * Porphyria * Presence of mitochondrial disease * No arterial cannula as standard clinical care during surgery

Design outcomes

Primary

Measure	Time frame
Mitochondrial PO2 versus Hb	—

Secondary

Measure	Time frame
SpHb, hemoglobin level in blood sampel, hemodynamic and respiratory parameters as they are commonly recorded during general anesthesia.	—

Countries

Netherlands

Outcome results