Nailfold videocapillaroscopy in juvenile (systemic) autoimmune diseases

Nailfold videocapillaroscopy in juvenile (systemic) autoimmune diseases - Capillaroscopy in juvenile autoimmunity

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON50708

Enrollment

400

Registered

2017-10-16

Start date

2017-10-22

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

autoimmunity lupus Raynaud

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Healthy children, 6-18 years old2. Pediatric patients =18 years old, with a diagnosis childhood-onset SLE / RP, diagnosed before the age of 18#*¶*l/+

Exclusion criteria

Exclusion criteria: Lack of written informed consent

Design outcomes

Primary

Measure	Time frame
NVC measurements consist of describing the following variables per 1 mm image (4 images per finger, digits 2-5 on both sides): - Density: number of capillaries per mm (mean 9, range 6-12) - Abnormal shapes described as not-hairpin/tortuous/crossing (1) - Capillary apex maximum diameter (20-50 mcm described as enlarged, >50mcm described as giant capillary) - Large micro-hemorrhages (pathological bleedings with apical cap-like appearance) - Small multiple point-shaped hemorrhages surrounding the capillary loop (extravasations) Specific endpoint for study 3: diagnosis of a (systemic) autoimmune disease.	—

Measure

Time frame

NVC measurements consist of describing the following variables per 1 mm image (4 images per finger, digits 2-5 on both sides): - Density: number of capillaries per mm (mean 9, range 6-12) - Abnormal shapes described as not-hairpin/tortuous/crossing (1) - Capillary apex maximum diameter (20-50 mcm described as enlarged, >50mcm described as giant capillary) - Large micro-hemorrhages (pathological bleedings with apical cap-like appearance) - Small multiple point-shaped hemorrhages surrounding the capillary loop (extravasations) Specific endpoint for study 3: diagnosis of a (systemic) autoimmune disease.

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Countries

Netherlands

Outcome results