Depression and personality disorders
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Age 18-65 years DSM-IV diagnosis of a major depressive episode or dysthymia and DSM-IV diagnoses of one or more personality disorders
Exclusion criteria
Exclusion criteria: - Non-Dutch speakers/readers -Psychotic symptoms, bipolar disorder or current extreme substance dependence. -Immediate intensive treatment or hospitalization is needed, e.g. acute suicidality. - Pregnancy or other reasons why trial demands can*t be met - Use of medication that influences mental functioning: antipsychotics, moodstabilizers, benzodiazepines > 30mg oxazepam or equivalent per day.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression severity (BDI-II) will be the main outcome measure. The proportion of patients that achieve reliable and clinically significant improvement at termination and follow-up will we calculated on the outcome measure (BDI-II) for both conditions, using the method by Jacobson and Truax. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures are personality changes, cost-effectiveness and quality of life. Also process variables will be analysed in order to find change mechanisms in psychotherapy. One of the factor that will be investigated is the working alliance and the level of discourse in SPSP. Moderating factors like the type of therapy will also be analysed. | — |
Countries
Netherlands