na IC opname intensive care recovery post-ICU
Conditions
Interventions
One group receives daily 2 sachets of 22 g porcine protein, so in total 44 g
per day.
The other group receives daily 2 sachets of 21 g maltodextrin, so in total 42 g
per day.
Sponsors
Ziekenhuisvoorzieningen Gelderse Vallei
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Age >= 18 years 2. Living at home before hospital admission 3. Minimum ICU stay of 72 h 4. Informed consent
Exclusion criteria
Exclusion criteria: 1. MRC sum score = at ICU discharge 2. Barthel Index 173 mcmol/l (renal dysfunction) 5. Inclusion in other intervention trial since ICU admission 6. Inflammatory Bowel Disease 7. Zwangerschap 8. Underlying disease in which in the eyes of the attending physician, the protein or carbohydate supplement could form a risk for the patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A composite endpoint of hand grip strength, Hand-held Dynamometer m. quadriceps fem, Hand-held Dynamometer m. biceps brachii and 6 Minute walking test at t=2 (hospital discharge), t=3 (day 42 = end of intervention) and t=4 (3 months follow-up). | — |
Secondary
| Measure | Time frame |
|---|---|
| - Handgrip strength assessed with Jamar dynamometer at T=3. - Muscle strength leg assessed with HHD m. quadriceps fem. at T=3. - Muscle strength arm assessed with HHD m. biceps brachii at T=3. - Exercise capacity assessed with 6 Minute Walking Distance at T=3. - Lower extremity muscle function assessed with TCST at T=3. - CPAx at T=2. - MRCsum at T=2, T=3 and T=4. - Barthel score at T=3. - Rockwood Clinical Frailty Scale at T=3. - Body composition (BIA) at T=2, T=3 and T=4. - Plasma AA concentrations at T=3. - ICU readmission after ICU discharge - Hospital readmission after hospital discharge - Overall survival status | — |
Countries
Netherlands
Outcome results
None listed