dental implant bone loss Dental implant inflammation
Conditions
Interventions
Surgical procedure:
" All surgeries are performed under local anaesthesia.
" After a crestal incision and intrasulcular incision at the adjacent teeth, a
buccal and lingual full-thickness mucoperiost
Sponsors
Vrije Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Periodontally compromised patients having a history of proximal attachment loss of > 5mm in > 30% of teeth present - Enrolled in a supportive periodontal therapy (SPT) program after active periodontal treatment - Requirement of two single-unit FPDs supported by two implants in mandibular premolar/molar area - Adjacent tooth/teeth must have natural root(s) - In antagonist jaw natural teeth, partial prosthesis, or implants supported (partial) prosthesis in contact with planned FPD - History of edentulism in planned implant areas > 4 months - At planned implant areas, a minimum of 11 mm bone in vertical dimension and minimum of 6 mm in horizontal dimension available. Assessment included CBCT scan when required, judged by investigator - Acquiring of a primary stable implant situation assumed by investigator
Exclusion criteria
Exclusion criteria: - History of local radiotherapy to the head and neck region - History of chemotherapy 10 cigarettes a day - Uncontrolled diabetes mellitus - Known or suspected current malignancy - Pregnancy at time of inclusion - Alcohol or drug abuse - Any systemic or local disease that would compromise postoperative healing and/or osseointegration - Need for systemic bisphosphonates, corticosteroids or any other medication that would compromise postoperative healing and/or osseointegration - Presence of active clinical periodontal disease expressed by probing pocket depths > 5 mm and bleeding on probing - History of necrotic or rapid progressive periodontitis - Untreated caries and/or endodontic disease - Previous implant loss - Previous bone augmentation in planned implant area - Incapability of performing oral hygiene measures as a result of physical or mental disorders - During any period of the study, if any mandatory procedures and measurements are missing by the investigator, that dataset of that subject will be removed from the final results.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is the radiographical implant mean marginal bone level (MBL) alteration on the mesial and the distal site 36 months after delivery of the FPDs. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are implant survival, implant stability, marginal peri-implant soft tissue conditions (amount of plaque, bleeding on probing and pocket probing depths) and peri-implant microbiological compilation. | — |
Countries
Netherlands
Outcome results
None listed