decrease in musscle mass and function Sarcopenia
Conditions
Interventions
Subjects will be randomly assigned to one of the three groups. Daily
supplementation will be consumed at two doses/day (15 gram/dose), during
breakfast and after an exercise bout (or on days without
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - 60 years of older - Registered for the Nijmegen Four Days Marches 2022 - Able to understand and perform the study procedures
Exclusion criteria
Exclusion criteria: - Type I or Type II diabetes - Allergic or sensitive for milk proteins, or lactose intolerant - Allergic or sensitive for shell and shellfish, like shrimp - BMI >30kg/m2 - Diagnosed COPD - Currently treated for cancer - Diagnosed renal insufficiency - Diagnosed intestinal diseases influencing the uptake of protein (i.e. active inflammatory bowel disease, Crohn*s disease) - Consumption of other freely available protein supplements on their own during the total study period of about 4 months - Use of statins - Involved in a heavy resistance type exercise program
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is the muscle damage biomarkers Creatine Kinase in blood. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body composition, muscle strength, blood lipids and inflammatory markers will be measured as secondary study parameters. Via questionnaires the intake compliance, consumer satisfaction, muscle soreness, general physical activity- and food consumption patterns will be assessed. | — |
Countries
Netherlands
Outcome results
None listed