cardiac arrest
Conditions
Interventions
The patients will be randomized to either the immediate or delayed coronary
angiography and subsequent revascularisation group
Sponsors
Vrije Universiteit Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age > 18 Comatose patients (Glasgow coma score
Exclusion criteria
Exclusion criteria: Signs of STEMI on the ECG at the emergency department (including new LBTB or isolated ST depression in V1-V3 due to an true posterior infarct). Hemodynamic instability unresponsive to medical therapy (defined as a systolic blood pressure 4 hours (240 min from ROSC to screening Known inability to complete 90 day follow up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary end point of the study is 90-days survival | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints are 90-days survival with good, minor or moderate disability, myocardial injury measured by troponine and CK MB as area under the curve, occurrence off acute kidney injury, need for renal replacement therapy, time to target hypothermia, neurological status at ICU discharge and duration of inotropic support, left ventricular function on cardiac ultrasound or MRI (if available), functional performance measured with the RAND 36 questionnaire at 1 year and MACE and survival at 1 and 5 years. | — |
Countries
Netherlands
Outcome results
None listed