Comparison of two methods to improve the outcome of a ultrasound assisted fine needle aspiration biopsy (FNAB) of the thyroid gland.

Comparison of two methods to improve the outcome of a ultrasound assisted fine needle aspiration biopsy (FNAB) of the thyroid gland. - Thyrocore

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON50480

Enrollment

140

Registered

2022-03-02

Start date

2022-05-10

Completion date

Unknown

Last updated

2026-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thyroid lumb thyroid nodule

Interventions

The intervention consists of replacing one out of two standard thyroid FNAB*s (method A) with a thyroid FNAB using the CytoCore (method B).

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 18 years of older Patient qualifies for thyroid FNAC

Exclusion criteria

Exclusion criteria: 17 years or younger Patient does not qualifies for thyroid FNAC

Design outcomes

Primary

Measure	Time frame
There will be 140 FNAB*s with both methods (A and B). The methods are compared with each other on the basis of the diagnostic yield.	—

Secondary

Measure	Time frame
After 20 biopsies, the material is assessed again by the laboratory according to the Bethesda criteria and additional 'evaluability/quality' criteria. The laboratory will be blind to the method which is used to obtain de cytological material. The quality of the cytological material is a secondary endpoint.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Aug 25, 2026