Scoliosis three-dimensional deviation of the spinal axis
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Utrecht
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: - Patients diagnosed with adolescent idiopathic scoliosis - Presence of right convex main thoracic structural curve, either in Lenke type 1 or 2; - Female gender - Between 10-16 years of age - Cobb*s angle 20-40 degrees
Exclusion criteria
Exclusion criteria: - Skeletal maturity - Presence of any additional spine pathology such as spondylolysis or -listhesis, M. Scheuermann, congenital spinal abnormalities, spinal tumors and spinal trauma - Previous spinal surgery - Neurological symptoms, deficits or pathology - Syndromes associated with disorders of growth - Any contra-indication for MR Imaging
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Each MR scan will consist of a standard sagittal-only T2W, developed for IVD imaging. The IVDs of the spine between T1 and S1 will be scanned. The different parameters will be measured semi-automatically. The primary study parameters are changes in MRI timing, sensitivity, dynamic range, spatial distribution and morphological changes of the IVD during AIS progression. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary parameters are: 1. Correlation of the findings on MR-imaging with patient-reported outcome measurements using the SRS-22 questionnaire | — |
Countries
Netherlands
Outcome results
None listed