Hemodynamic characterization in hypertrophic cardiomyopathy after septal myectomy +/- mitral valve repair: a 4D-flow MRI study

Hemodynamic characterization in hypertrophic cardiomyopathy after septal myectomy +/- mitral valve repair: a 4D-flow MRI study - 4D-flow hemodynamics after septal myectomy in HCM

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON50330

Enrollment

Registered

2022-05-05

Start date

2022-11-05

Completion date

Unknown

Last updated

2025-09-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophic cardiomyopathy

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients that underwent septal myectomy +/- mitral valve repair due to hypertrophic cardiomyopathy

Exclusion criteria

Exclusion criteria: - Have underwent a cardiac reoperation after the initial surgical myectomy +/- MVR procedure - Have major comorbidity besides HCM - Are under the age of 18. - Have claustrophobia or another contra-indication for MRI. - Are not able to provide written informed consent.

Design outcomes

Primary

Measure	Time frame
The main study parameters are; - blood flow velocity - wall shear stress and energy loss over the aortic valve, the ascending aorta, the aortic arch and descending aorta	—

Secondary

Measure	Time frame
Routine MRI parameters; - enddiastolic and endsystolic volumes - stroke volume - ejection fraction	—

Countries

Netherlands

Outcome results