Upper respiratory tract problems requiring surgery
Conditions
Interventions
During the thirty minutes prior to the planned rigid laryngoscopy or
microlaryngeal surgery, during the procedure and during the 30 minutes after
the procedure transcutaneous CO2 levels will be meas
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
2 Years to 17 Years
Inclusion criteria
Inclusion criteria: Patient is up to 18 years of age. Indication to undergo a rigid laryngoscopic and/or microlaryngeal procedure. Adequate end-tidal carbon dioxide measurements are unlikely during the planned procedure.
Exclusion criteria
Exclusion criteria: Patient is older than 18 years of age Procedure is carried out while patient is intubated. Patient has a tracheal canula
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoint is the quantification of the effect of the clinical introduction of transcutaneous carbon dioxide monitoring during laryngoscopic and microlaryngeal procedures in children. Therefore, the main study parameter is the cumulative carbon dioxide load / shortage, as a fraction of the monitoring time and will be compared between the *pre* and *post* timeframes. | — |
Secondary
| Measure | Time frame |
|---|---|
| - The effect of adequate carbon dioxide management on the required fraction of inspired oxygen (FiO2) and the resulting SpO2 and cerebral NIRS levels (in patients in which cerebral NIRS measurements were performed). - The amount of use of different types of ventilation (e.g. manual, jet ventilation, spontaneous breathing) during these procedures in relation to the availability of tcPCO2 monitoring. The timing of the application of these ventilation methods is also compared. - The influence of patient age on measurements. - The influence of patient age on the effect of the availability of tcPCO2 monitoring. - The effects of carbon dioxide management without and with transcutaneous tcPCO2 monitoring on vital parameters such as blood pressure and heart rate. - The occurrence of skin effects during transcutaneous monitoring. - The effect of the availability of tcpCO2 monitoring on procedure length and time required to stabilise the patient between procedure steps. - The learning curve of anesthesiologists using transcutaneous carbon dioxide monitoring in terms of changing the timing of the application of different ventilation methods. - The consequences of the introduction of transcutaneous monitoring on clinical practice as evaluated by a questionnaire. - Comparison of the transcutaneously measured values to eventual blood gas samples that are taken as part of clinical care. - Comparison of the end-tidal CO2 values that are obtained in some instances to the tcPCO2 values. | — |
Countries
Netherlands
Outcome results
None listed