Immunogenic Properties of Heated and Glycated Cows Milk Protein Effect on Resolution of Cow*s Milk Allergy (iAGE study)

Immunogenic Properties of Heated and Glycated Cow*s Milk Protein * Effect on Resolution of Cow*s Milk Allergy (iAGE study) - iAGE

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON50280

Enrollment

200

Registered

2017-08-30

Start date

2018-02-15

Completion date

Unknown

Last updated

2024-04-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

koemelkallergie cow's milk allergy

Interventions

Treatment with heated-glycated cow's milk protein or placebo.

Eligibility

Age

2 Years to 11 Years

Inclusion criteria

Inclusion criteria: * Age: 3 up to 36 months. * Children with a positive DBPCFC with CM. This is defined as a well-documented DBPCFC with objective symptoms

Exclusion criteria

Exclusion criteria: * Current participation or participation in the last 12 months in a medical scientific interventional study for food allergy and/or with an investigational new drug. * Clinically significant immunological, cardiovascular or malignant disease.* * Inability to discontinue antihistamines for skin testing and oral food challenges. * Caregiver not able to read and understand the Dutch language. * Caregiver not able or willing to comply with the study procedures.

Design outcomes

Primary

Measure	Time frame
Development of tolerance (time to or percentage)	—

Secondary

Measure	Time frame
Adverse events.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)

Immunogenic Properties of Heated and Glycated Cow*s Milk Protein * Effect on Resolution of Cow*s Milk Allergy (iAGE study)