Early diagnosis of breast cancer: A multicenter, crOss sectional, study to assess microRNA expression in Nipple Aspirate Fluid, blood and tuMor material in women with primary brEast caNcer compared with healthy conTrols The ORNAMENT study

Early diagnosis of breast cancer: A multicenter, crOss sectional, study to assess microRNA expression in Nipple Aspirate Fluid, blood and tuMor material in women with primary brEast caNcer compared with healthy conTrols The ORNAMENT study - Early diagnosis of breast cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON50271

Enrollment

200

Registered

2016-08-17

Start date

2017-01-26

Completion date

Unknown

Last updated

2025-03-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer breast carcinoma

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Female age >=18 years histologically proven invasive breast carcinoma

Exclusion criteria

Exclusion criteria: Bilateral breast reduction with nipple graft Bilateral ablative breast surgery Pregnancy or lactation Active breast infection Having disseminated breast cancer

Design outcomes

Primary

Measure	Time frame
To compare microRNA expression in nipple fluid from the cancerous breast to microRNA expression in nipple fluid from the contralateral breast, the tumor material obtained at surgery and blood from the same patient.	—

Secondary

Measure	Time frame
To assess the microRNA expression levels in nipple fluid obtained just before treatment. This will be compared to the microRNA expression levels in nipple fluid already obtained from healthy controls.	—

Countries

Netherlands

Outcome results