Antisocial developmental Trajectories

Antisocial developmental Trajectories - Antisocial developmental Trajectories

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON50264

Enrollment

190

Registered

2009-12-09

Start date

2010-05-09

Completion date

Unknown

Last updated

2024-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

antisocial personality disorder - antisocial behavior

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Subject is in "very young offender"-cohort. Or control subjects; subjects with the same age and educational level as participants from the "very young offender" cohort (19-25 years)

Exclusion criteria

Exclusion criteria: Intraocular shreads of metal. Cardiac pacemaker, metal arterial clips, cochlear implant, implanted heart-valves, other implants or metal objects in the body (e.g. non-removable body piercings) not compatible with magnetic fields . Use of medication effecting brain functioning, except for short-acting medication that can be stopped for two days during the day of scanning and the day before. In the latter case, the physician of the participant will be consulted. Pregnancy.

Design outcomes

Primary

Measure	Time frame
Differential BOLD-response (i.e. blood flow to brain areas thought to reflect activation in these areas) in relevant neuronal networks during fear conditioning as well as during reward/punishment anticipation and outcome. Amendement genetica: Genetic variation (Single Nucleotide Polymorphisms, SNPs), gene expression data. ' Amendement Wave 5': (1) Difierenttal BOLD-æsponse in relevant neuronal networks including self-concept evaluation, vicarious reward leaming and impulse control, {2) developmental changes in brain structure and (3) stability of antísocial behaviour over time.* 'EEG / Justice amendment': (addition to wave 5): EEG recording, criminal recidivism based on official registration systems [police / justice] and cyber crime.	—

Measure

Time frame

Differential BOLD-response (i.e. blood flow to brain areas thought to reflect activation in these areas) in relevant neuronal networks during fear conditioning as well as during reward/punishment anticipation and outcome. *Amendement genetica*: Genetic variation (Single Nucleotide Polymorphisms, SNPs), gene expression data. ' Amendement Wave 5': (1) Difierenttal BOLD-æsponse in relevant neuronal networks including self-concept evaluation, vicarious reward leaming and impulse control, {2) developmental changes in brain structure and (3) stability of antísocial behaviour over time.* 'EEG / Justice amendment': (addition to wave 5): EEG recording, criminal recidivism based on official registration systems [police / justice] and cyber crime.

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Secondary

Measure	Time frame
Fear conditioning (CS-US contingency in terms of skin conductance levels, arousal and emotional valence), reward- and punishment-anticipation, self-reported criminal recidivism. Amendement genetica:networks of functionally related genes, epigenetic changes. 'Amendement Wave 5': behavior on affective control, social fear learing and moral learning; self-reported criminal recidivism, testosterone. 'Amendement EEG/Justice': -	—

Measure

Time frame

Fear conditioning (CS-US contingency in terms of skin conductance levels, arousal and emotional valence), reward- and punishment-anticipation, self-reported criminal recidivism. *Amendement genetica*:networks of functionally related genes, epigenetic changes. 'Amendement Wave 5': behavior on affective control, social fear learing and moral learning; self-reported criminal recidivism, testosterone. 'Amendement EEG/Justice': -

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Countries

Netherlands

Outcome results