pancreas pancreatic cancer pancreatic lesions
Conditions
Interventions
None listed
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients scheduled for EUS-FNA, due to a suspect lesion of the pancreas
Exclusion criteria
Exclusion criteria: - Patients with age under 18 years - Patients who object to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The shape of the spectra and the optical absorption coefficients over a broad wavelength range will be used to distinguish pancreatic tumors and benign pancreatic tissue. To extract and quantify physiological information from the obtained spectra, such as blood volume fraction and tissue oxygenation, a validated mathematical model, based on the knowledge of the absorption spectra of the chromophores, will be used. Therefore, we need to determine the serum bilirubin and hemoglobin, before the EUS-FNA is performed, which is part of the clinical workflow ('zorgpad pancreas'). The obtained spectra will be linked to final cytological analysis. | — |
Secondary
| Measure | Time frame |
|---|---|
| The diagnostic accuracy (including sensitivity, specificity, negative predictive value and positive predictive value) of one or more combined wavelengths specific for pancreatic tumor tissue will be calculated after comparison to cytological and final diagnosis. | — |
Countries
Netherlands
Outcome results
None listed