botgezondheid Bone health osteoporosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: * Elite cyclists status * Age *16 and *35 years. * Willing to give blood samples * Willing to comply with study procedures
Exclusion criteria
Exclusion criteria: * Blood donation during the study period * Severe allergy to nuts or intolerance to gluten, as supplements are being produced in factory that may have used nuts or gluten previously * Use of antibiotics in the past month * Medical condition that can interfere with the study outcome (i.e. cardiovascular disease, pulmonary disease, rheumatoid arthritis, orthopaedic disorders, renal disease, liver disease, diabetes mellitus, inflammatory disease, cognitive impairment, and thyroid or parathyroid disease)) * Use of medications known to interfere with selected outcome measures (i.e. corticosteroids, , statins, fenofibrate, beta-blocker) * (Chronic) injuries of the locomotor system that can interfere with the intervention. * Current participation in another biomedical research study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lumbar spine bone mineral density. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood parameters of bone turnover: Procollagen type I N propeptide (P1NP), carboxy-terminal crosslinking telopeptide of type I collagen (CTX-I). Countermovement jumps will assess the effect of the intervention on jump height as a marker of lower body power. | — |
Countries
Netherlands