no health condition is addressed in the research, and healthy volunteers who are occasional cannabis users will be recruited n.a.
Conditions
Interventions
Participants will undergo 4 experimental conditions, in which they receive a
fixed dose of Bedrocan cannabis in different forms (granulate, powder and
yellowcake) or placebo. In each condition, the
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Occasional cannabis users (>10 lifetime exposures and
Exclusion criteria
Exclusion criteria: • History of drug abuse (other than the use of cannabis) or addiction (determined by the medical questionnaire, drug questionnaire and medical examination) • Pregnancy or lactation (pregnancy test, if needed) • Hypertension (diastolic > 90; systolic > 140) • Current or history of psychiatric disorder (determined by the medical questionnaire and medical examination) • Liver dysfunction • Any serious prior adverse response to cannabis • History of cardiac dysfunctions (e.g. arrhythmia, ischemic heart disease)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The inhalation process and the overall satisfaction with the use of the IMPs will be assessed by the means of Likert scales. | — |
Secondary
| Measure | Time frame |
|---|---|
| Subjective drug effects will be measured by a series of VAS/Bowdle questionnaire/CADDS. The assessment of the quality of the IMPs by participants will be measured by a series of Likert scales. Cognition will be assessed by a computerized test battery. Memory, i.e. sensitivity to go along with suggested self-incriminating statements will be assessed using an adjusted false confession paradigm. | — |
Countries
Netherlands
Outcome results
None listed